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ANGII-1: Certified reference material of angiotensin II

From National Research Council Canada

Alternative titleANGII-1 : Matériau de référence certifié de l'angiotensine II
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DOIResolve DOI: https://doi.org/10.4224/crm.2019.angii-1
AuthorSearch for: 1ORCID identifier: https://orcid.org/0000-0002-2290-0101; Search for: 1; Search for: 1ORCID identifier: https://orcid.org/0000-0002-7265-9344; Search for: 1; Search for: 1; Search for: 1ORCID identifier: https://orcid.org/0000-0002-1167-6474; Search for: 1ORCID identifier: https://orcid.org/0000-0002-2377-2615; Search for: 1ORCID identifier: https://orcid.org/0000-0002-3349-5535
Affiliation
  1. National Research Council of Canada
Format3D, Material
SubjectCanadian reference material; ANGII-1; angiotensin II; trifluoroacetic acid; peptide standard
Abstract
ANGII-1 is a certified reference material (CRM) for the synthetic peptide angiotensin II (DRVYIHPF) and the trifluoroacetic acid (TFA) content. This material, distributed in 25 mg units, is intended for instrument calibration, method development, and validation for peptide hydrolysis experiments. Certified values for the mass fraction of angiotensin II and TFA have been established and information values for the mass fraction of water and related peptide impurities are provided.
Analytes
AnalyteQuantityValueExpanded uncertaintyUnitType
angiotensin IImass fraction6919mg/gcertified
trifluoroacetic acidmass fraction2496mg/gcertified
watermass fraction34mg/ginformation
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PublisherNational Research Council of Canada
Copyright statement
  • © 2019 National Research Council of Canada
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References
View items (4)
  1. Melanson, Jeremy E., Marie-Pier Thibeault, Bradley B. Stocks, Donald M. Leek, Garnet McRae, and Juris Meija. ‘Purity Assignment for Peptide Certified Reference Materials by Combining QNMR and LC-MS/MS Amino Acid Analysis Results: Application to Angiotensin II’. Analytical and Bioanalytical Chemistry 410, no. 26 (24 August 2018): 6719–31. .
  2. Stocks, Bradley B., Marie-Pier Thibeault, Juris Meija, and Jeremy E. Melanson. ‘Assessing MS-Based Quantitation Strategies for Low-Level Impurities in Peptide Reference Materials: Application to Angiotensin II’. Analytical and Bioanalytical Chemistry 410, no. 26 (21 August 2018): 6963–72. .
  3. ‘Evaluation of Measurement Data — Guide to the Expression of Uncertainty in Measurement’, 2008. .
  4. Veen, Adriaan M. H. van der. ‘Bayesian Analysis of Homogeneity Studies in the Production of Reference Materials’. Accreditation and Quality Assurance 22, no. 6 (2 November 2017): 307–19. .
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CollectionCanadian Reference Materials and Methods
Record identifier06b0f5e8-16e2-4b69-aa89-0aac2d1fb071
Record created2019-09-19
Record modified2024-08-24
Date modified: